Welcome to Historic Defiance

There are many important people and events that have made history in and around Defiance. Check out the Daniel Boone Home, the Hays Home, bike the renowned Katy Trail and examine historical markers throughout the area, or follow the river road to take in the unspoiled beauty of the area.

The Defiance area is rich in history, from the native Ozark Tribe and Daniel Boone to the railroad, river lore, and modern America.  There is something to discover for everyone.

Defiance, MO is the gateway to Historic Missouri Wine Country.  The Defiance area offers a spectacular destination for weekend retreats, weddings, history exploration, or recreation, and is a wonderful place to live.  Located just west of the St. Louis metro area, Defiance is easy to visit and hard not to love.  Come explore the Defiance area, and plan your next outing with us!